Prompt

I want to create an image that shows the challenges of antibody-drug conjugates (ADCs) and how single-cell multi-omics can address them. I want to focus on target identification and mapping of different signaling pathways. Challenges: - Antigen heterogeneity - Variable internalization & trafficking - Off-target cytotoxicity - Adaptive signaling rewiring - Model–patient disconnect How single-cell multi-omics can help - Single-cell RNA-seq / ATAC-seq: Identify subpopulations expressing antigen or resistance pathways - CITE-seq / REAP-seq: Link antigen density to transcriptional response and payload sensitivity - Multi-omic integration: Model how antigen expression, trafficking, and signaling jointly define ADC MoA. Can you try to integrate these information into one or two images?

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